Maximum 25mg empagliflozin + 1000mg metformin XR strength

Strongest possible A1C reduction with true once-daily dosing

Maximum weight loss & blood pressure lowering

Superior protection against heart failure & kidney disease progression

Extended-release technology for excellent stomach tolerance

1. Take one tablet once daily with your evening meal to minimise stomach upset
2. Swallow whole with water – never crush, chew or break the tablet
3. Take at the same time every day for steady 24-hour control
4. Continue prescribed diet, exercise and regular blood glucose monitoring
5. If you miss a dose, take it as soon as remembered unless it’s almost time for the next dose

Q1: Why is 25/1000mg the strongest combination?
A1: It combines the highest empagliflozin dose (25mg) + maximum metformin XR dose for the most powerful A1C, weight and cardio-renal effects in one pill.

Q2: How much weight can I expect to lose?
A2: Most patients lose 4–7 kg over several months due to the high empagliflozin dose.

Q3: How much does it lower A1C?
A3: Up to 2.0–2.5% reduction – one of the strongest oral combinations available.

Q4: Is heart & kidney protection even stronger at 25mg?
A4: Yes – clinical trials show incrementally greater reduction in heart failure and kidney events at 25mg vs lower doses.

Q5: Is the 1000mg extended-release still gentle on the stomach?
A5: Much gentler than regular metformin; taking with food further reduces any GI discomfort.

• Strictly under doctor supervision with regular kidney function, vitamin B12 and lactic acid monitoring
• Drink plenty of fluids to prevent dehydration, urinary or genital infections
• Stop immediately and seek emergency care if lactic acidosis symptoms occur (muscle pain, breathing difficulty, extreme drowsiness)
• Not for type 1 diabetes or diabetic ketoacidosis
• Contraindicated in severe renal impairment (eGFR <30) or severe liver disease
• Discontinue at least 3–4 days before major surgery or iodinated contrast scans