• Maximum-strength 12.5mg empagliflozin + 1000mg metformin XR
• Superior 24-hour glucose control with excellent GI tolerance
• Proven to reduce heart failure risk & slow kidney disease
• Greater weight loss & blood pressure reduction
• True once-daily convenience

1. Take one tablet once daily with your evening meal to reduce stomach upset
2. Swallow whole with water – never crush, chew or break
3. Take at the same time every day for steady 24-hour coverage
4. Continue diet, exercise and regular blood glucose checks
5. If you miss a dose, take it as soon as remembered unless it’s almost time for the next one

Q1: Why choose 12.5/1000mg strength?
A1: It gives stronger glucose lowering, more weight loss, and maximum cardio-renal protection in one tablet.

Q2: How much weight can I lose?
A2: Most patients lose 3–6 kg over several months due to empagliflozin’s calorie-loss effect.

Q3: How much does it lower A1C?
A3: Typically 1.7–2.3% reduction – among the strongest oral combinations available.

Q4: Is the heart & kidney protection stronger at 12.5mg?
A4: Yes – higher empagliflozin dose provides incrementally greater cardio-renal benefits.

Q5: Is extended-release easier on the stomach?
A5: Yes – dramatically reduces nausea/diarrhoea compared to immediate-release metformin 1000mg.

• Use only under doctor supervision with regular kidney function, vitamin B12, and lactic acid monitoring
• Drink plenty of fluids to prevent dehydration or urinary/genital infections
• Stop immediately and seek emergency help if lactic acidosis symptoms occur (muscle pain, breathing trouble, extreme drowsiness)
• Not for type 1 diabetes or diabetic ketoacidosis
• Contraindicated in severe renal impairment (eGFR <30) or severe liver disease
• Discontinue at least 3 days before major surgery or iodinated contrast scans