• Rapid and reliable suppression of gastric acid
• Useful when oral PPIs are not possible
• Flexible administration: injection or infusion
• Well-established IV dosing protocol
• Proven safety and efficacy in hospital settingsRapid and reliable suppression of gastric acid
• Useful when oral PPIs are not possible
• Flexible administration: injection or infusion
• Well-established IV dosing protocol
• Proven safety and efficacy in hospital settings

1. Reconstitute the vial with 5 mL of 0.9% sodium chloride injection.
2. Withdraw the full 5 mL of the reconstituted solution.
3. Administer intravenously over at least 3 minutes.
4. If required as an infusion, dilute further (e.g., to 50 mL) and infuse over 10–30 minutes.
5. Discard any unused solution after 12 hours at room temperature.

Q: What is this injection used for?
A: It’s used for acid-related gastrointestinal issues in patients who cannot take oral PPIs.

Q: How quickly does it work?
A: Because it’s given IV, acid suppression starts faster than with oral medications.

Q: Can I use it long-term?
A: It's generally for hospital or short-term use — long-term IV use requires medical supervision.

Q: What are common side effects?
A: Possible side effects include headache, nausea, diarrhea, or injection-site reactions.

Q: Is dose adjustment needed for liver problems?
A: Yes — in severe liver impairment, dosing needs special consideration.

• Reconstitute only with 5 mL of 0.9% sodium chloride using aseptic technique.
• Administer the injection over at least 3 minutes; do not inject faster.
• Use the reconstituted solution within 12 hours at room temperature (≤ 30 °C).
• Always flush the IV line before and after Nexum with 0.9% NaCl, Lactated Ringer’s, or 5% dextrose.
• Monitor patients with liver impairment, as esomeprazole metabolism may be affected.