• Provides systemic inflammation control for psoriasis and psoriatic arthritis rather than just topical relief.
• May help reduce skin lesion severity, plaque burden and joint symptoms, improving quality of life.
• Oral once-/twice-daily dosing offers flexibility and convenience compared to injectable biologics.
• Acts through a novel mechanism (PDE4 inhibition) providing an alternative for patients intolerant of biologics or conventional immunosuppressants.
• Under proper supervision, supports long-term disease management and may reduce flare frequency.

1. Take one tablet of Kuniz 30 mg orally with water—typically twice daily (morning and evening) as prescribed by your doctor.
2. A dose titration schedule is often followed in the first 5 days to reduce gastrointestinal symptoms: e.g., 10 mg once on Day 1, 10 mg twice on Day 2, ramping up to 30 mg twice daily by Day 6.
3. Swallow the tablet whole; do not crush, split or chew unless directed.
4. Continue long-term use as advised; do not stop abruptly without consulting your physician as symptoms may recur.
5. Attend follow-up consultations regularly to monitor response, side-effects and adjust therapy accordingly.

1. What conditions does Kuniz Tablet treat?
It is indicated for moderate-to-severe plaque psoriasis and active psoriatic arthritis in adults.

2. When can I start seeing improvement?
Skin or joint symptoms may show improvement after a few weeks; full benefits often take several months of consistent use under medical supervision.

3. Can it be used in children?
Safety and effectiveness in children under 18 years are not established; use only under specialist supervision.

4. What are common side-effects I should watch for?
Common side-effects include nausea, diarrhea, headache, upper respiratory infections. Serious warnings include weight loss and mood changes.

5. Do I need to avoid anything while taking this drug?
Inform your doctor about other medications, especially strong CYP450 inducers (which may reduce efficacy). Also monitor your mood, weight and general health regularly.

• Must be used only by prescription from a qualified dermatologist or rheumatologist.
• Monitor for weight-loss, mood changes (including depression or suicidal thoughts), and gastrointestinal side-effects like diarrhea or nausea.
• Not recommended in pregnancy or for breastfeeding without specialist consultation; use effective contraception.
• Use caution when co-administered with strong CYP450 inducers (e.g., rifampin) which may reduce efficacy.
• Store in a cool, dry place as per packaging, and keep out of reach of children.