• Highest single-tablet Levodopa dose for maximum daily control
• Extends “on” time and significantly reduces “off” episodes
• Minimises pill burden compared to separate Levodopa/Carbidopa + Entacapone
• Improves overall motor function and quality of daily living
• Proven efficacy in advanced Parkinson’s with wearing-off phenomenon

1. Take exactly as directed by your neurologist, typically 3–5 times daily at regular intervals
2. Swallow the tablet whole with water – never crush, chew, or split
3. Space doses evenly and avoid high-protein meals close to dosing (protein can interfere with absorption)
4. If you miss a dose, take it as soon as remembered unless close to the next scheduled dose
5. Attend regular neurological reviews for dose optimisation and dyskinesia monitoring

Q1: When is the 200/50/200mg strength usually prescribed?
A1: When lower strengths no longer provide adequate “on” time and motor fluctuations become troublesome.

Q2: Will this higher dose cause more dyskinesia?
A2: It can initially increase involuntary movements; your neurologist will fine-tune timing and dose to balance benefits.

Q3: How many tablets will I need per day?
A3: Most patients take 3–5 tablets daily, significantly fewer than taking separate medications.

Q4: Is dark-coloured urine or sweat normal on Dopacone?
A4: Yes – harmless reddish-brown discoloration of body fluids is common and not a cause for concern.

Q5: Can I take it with food?
A5: Yes, but low-protein meals are best; high-protein foods can reduce Levodopa absorption.

• Contraindicated in narrow-angle glaucoma, suspicious skin lesions, or history of melanoma
• Avoid abrupt withdrawal – may trigger neuroleptic malignant-like syndrome
• May cause sudden sleep episodes or severe drowsiness – refrain from driving/machinery
• Watch for compulsive behaviours (gambling, binge eating, hypersexuality)
• Use caution in severe heart, liver, kidney, or psychiatric conditions
• Store below 30°C, protected from light and moisture; keep away from children