• Highest-dose single-pill triple therapy available
• 35–45 mmHg average systolic BP reduction
• Goal <130/80 in >80% of high-risk patients
• Proven stroke & heart-attack risk reduction
• 28-day exact monthly pack

1. One Covam Plus 10/160/25mg tablet every morning
2. Swallow whole – do not crush or split
3. Same time daily for rock-solid 24-hour control
4. Usually final step before adding spironolactone or switching to injectable therapy

Q1: When is this triple combo prescribed instead of dual therapy?
A1: Office BP ≥160/100, resistant hypertension, diabetes + proteinuria, post-stroke, or known coronary disease – anywhere maximum protection is needed fast.

Q2: How much stronger than Amlodipine/Valsartan 10/160 alone?
A2: Adds another 12–18 mmHg systolic drop thanks to the 25mg HCTZ – often the difference between controlled and uncontrolled.

Q3: Will I get swollen ankles from the high amlodipine?
A3: Possible in 10–15% (usually mild); valsartan + diuretic actually reduce the swelling risk compared to amlodipine alone.

Q4: Safe in chronic kidney disease?
A4: Yes – licensed down to eGFR ≥30; valsartan component is kidney-protective.

Q5: Why 28 tablets instead of 30?
A5: Exact 4-week European blister – perfect monthly cycle with zero leftover tablets.

• Take once every morning – with or without food
• Stand up slowly to avoid dizziness in first week
• Monitor kidney function & potassium at 2–4 weeks
• Not during pregnancy (category D)
• Keep away from children