• Delivers the strongest possible HbA1c reduction with pioglitazone
• Maximizes insulin sensitivity and reduces liver glucose output
• Once-daily maximum dose for simplified intensive therapy
• Helps preserve pancreatic beta-cell function longer
• Supports cardiovascular protection in type 2 diabetes

1. Take one Piozer 45mg Tablet once daily, with or without food, exactly as prescribed
2. Swallow the tablet whole with water; do not crush, chew, or split
3. Take at the same time every day for consistent blood levels
4. If you miss a dose, take it as soon as remembered unless near the next dose—never double up
5. Continue regular blood glucose testing, healthy eating, and physical activity

Q1: When is Piozer 45mg prescribed?
A1: It’s the maximum dose used when 15mg or 30mg doesn’t achieve target HbA1c levels.

Q2: Can it be combined with insulin or other diabetes medicines?
A2: Yes, it’s frequently combined with metformin, sulfonylureas, or insulin for enhanced control.

Q3: How much can HbA1c drop with the 45mg dose?
A3: Studies show reductions of up to 1.5–2% when added to existing therapy.

Q4: Will I gain weight on Piozer 45mg?
A4: Some weight increase is possible due to fluid retention and fat redistribution; your doctor will monitor.

Q5: How soon will I notice results?
A5: Peak effect is reached after 8–12 weeks of continuous daily use.

• Not indicated for type 1 diabetes or diabetic ketoacidosis
• Contraindicated in active bladder cancer or history of bladder cancer; discuss risk with your doctor
• Regular liver function tests, eye exams, and heart monitoring are essential
• May cause fluid retention—report sudden weight gain, swelling, or shortness of breath immediately
• Increased fracture risk in women; use caution if you have osteoporosis
• Store below 25°C in a dry place, protected from light