• Dual attack: fixes insulin resistance + boosts insulin release
• Exceptional fasting plasma glucose reduction
• Metformin-free option for GI-sensitive patients
• Proven in long-duration & South-Asian diabetes profiles
• Single morning tablet simplicity

1. One Zoliget 15/2mg tablet every morning with first meal
2. Swallow whole with water
3. Never skip or delay meals after taking
4. Doctor may step down to 15/1mg or up to 30/4mg depending on response

Q1: Why combine pioglitazone with glimepiride instead of metformin?
A1: Offers powerful fasting glucose lowering in metformin-intolerant patients and gives extra beta-cell stimulation when insulin secretion is declining.

Q2: How big is the hypo risk with the 2mg glimepiride dose?
A2: Moderate – about 8–12% of patients experience mild lows (usually avoided by eating regular meals).

Q3: Is it useful in PCOS or fatty liver?
A3: Yes – pioglitazone component improves ovulation rates and reduces liver fat even without metformin.

Q4: When is 15/2mg preferred over lower or higher strengths?
A4: Ideal balance for most adults needing moderate secretagogue effect with full insulin-sensitising benefits.

Q5: Any weight change?
A5: Average +2–4 kg gain in first year (fluid + fat redistribution); often stabilises or reverses with diet.

• Take once every morning with breakfast
• Risk of mild hypoglycaemia (especially if meals skipped) – carry glucose
• Regular weight & oedema check in first 6 months
• Contraindicated in heart failure or active liver disease
• Keep away from children