• Maximum 1000mg metformin XR for intensive glucose control
• Empagliflozin adds proven heart failure & kidney protection
• Promotes modest weight loss & lowers blood pressure
• Extended-release = better stomach tolerance
• Single daily tablet simplifies treatment

1. Take one tablet once daily with your evening meal to minimise stomach upset
2. Swallow whole with water – never crush, chew or split
3. Take at the same time every day for consistent control
4. Continue diet, exercise and regular blood glucose checks
5. If you miss a dose, take it as soon as remembered unless it’s almost time for the next dose

Q1: Why is this strength good for me?
A1: The 1000mg extended-release metformin gives maximum glucose-lowering power while empagliflozin adds heart/kidney protection and weight loss.

Q2: Will I still lose weight even with only 5mg empagliflozin?
A2: Yes – most patients lose 1–3 kg thanks to calorie loss in urine.

Q3: How much does it lower A1C?
A3: Usually 1.5–2.2% reduction, especially effective in patients with higher baseline levels.

Q4: Do I get the same heart and kidney benefits at 5mg?
A4: Yes – empagliflozin’s cardio-renal protection is proven even at the 5mg/10mg doses.

Q5: Is the 1000mg metformin hard on the stomach?
A5: Extended-release form is much gentler than regular metformin; taking with food further reduces side effects.

• Use only under medical supervision with regular kidney function and vitamin B12 monitoring
• Stay well-hydrated to reduce risk of dehydration or urinary infections
• Stop immediately and seek urgent help if lactic acidosis symptoms occur (muscle pain, breathing difficulty, extreme drowsiness)
• Not for type 1 diabetes or diabetic ketoacidosis
• Avoid in severe renal impairment (eGFR <30) or active liver disease
• Discontinue before major surgery or iodinated contrast scans