• Maximum oral sulfonylurea strength in one tablet
• Strongest possible 24-hour glucose control
• Significant HbA1c reduction when lower doses fall short
• Convenient once-daily morning dosing
• Proven efficacy and safety profile

1. Take one Getryl 4mg tablet once daily with breakfast or first main meal
2. Swallow whole with water – do not crush or chew
3. Never skip or delay meals after dosing
4. Monitor blood glucose several times daily when starting or titrating
5. Regular HbA1c, kidney, and liver function tests required

Q1: When does a doctor prescribe the full 4mg strength?
A1: When 3mg no longer achieves target HbA1c and the patient wants to delay insulin as long as possible.

Q2: Is hypoglycemia frequent at 4mg?
A2: Risk is highest at this dose – regular meals and self-monitoring are essential.

Q3: Can I split 4mg into two 2mg tablets?
A3: No – Glimepiride is formulated for once-daily use; splitting reduces effectiveness.

Q4: How much extra lowering can I expect from 4mg vs 3mg?
A4: Typically an additional 0.5–0.8% HbA1c reduction.

Q5: Is long-term use of 4mg safe?
A5: Yes – large studies confirm cardiovascular safety when used correctly.

• Not for type 1 diabetes or diabetic ketoacidosis
• Highest hypoglycemia risk among Glimepiride strengths – always carry fast-acting sugar
• Strictly avoid alcohol – greatly increases low-sugar episodes
• Modest weight gain common – combine with strict diet/exercise
• Use with caution in elderly or mild kidney/liver impairment
• Store below 30°C; keep away from children