• Fastest possible gout flare termination
• Classic 1mg + 0.5mg loading regimen in exact tablet strength
• Proven effective for over 50 years
• Can be used for both attack treatment and prevention
• Maximum power when speed matters most

For acute gout attack (standard regimen):

1. At first twinge: take 2 tablets (1mg total)
2. 1 hour later: take 1 more tablet (500mcg)
3. Then 1 tablet every 6–8 hours until pain completely gone
4. Do not exceed 6mg (12 tablets) in any 4-day period

Prevention:
Doctor may prescribe 1 tablet once or twice daily long-term (especially when starting allopurinol/febuxostat)

Q1: Why choose 500mcg tablets instead of 250mcg?
A1: Allows classic high-loading dose (1mg + 0.5mg) proven most effective for severe, established flares.

Q2: How fast does it work?
A2: Most patients feel major pain relief within 12 hours; full resolution in 24–48 hours.

Q3: Is the 500mcg tablet still widely used?
A3: Yes – remains the standard strength in most countries and the preferred dose for rapid control of intense attacks.

Q4: Can I use it to prevent attacks?
A4: Yes – 500mcg once or twice daily is licensed for long-term prophylaxis.

Q5: Any difference in side effects vs 250mcg?
A5: Same molecule – diarrhoea risk is dose-dependent, so low-dose prevention (500mcg daily) is very well tolerated.

• Take with or without food
• Classic acute regimen: 2 tablets (1mg) immediately, then 1 tablet (500mcg) after 1 hour, then 500mcg every 6–8 hours until pain gone (max 6mg per attack)
• Reduce dose in kidney/liver disease or if on strong CYP3A4 inhibitors
• Stop if severe diarrhoea or vomiting occurs
• Keep away from children