• Stops acute gout attacks within 12–24 hours
• Prevents >80% of future flares when taken nightly
• First-line prophylaxis with allopurinol/febuxostat
• Low-dose 250mcg = excellent stomach tolerance
• Gold-standard gout medicine for over 50 years

Acute attack:

• First hour: 2 tablets (500mcg)
• After 12 hours: 1 tablet
• Then 1 tablet every 12–24 hours until pain gone (max 6 tablets per attack)

Prevention (most common):

• One Xeticam 250mg tablet every night long-term

Q1: Is 250mcg the usual dose worldwide?
A1: Yes – 0.5–0.6mg is standard; 250mcg tablets allow exact dosing with fewer GI side effects.

Q2: When do I take it to prevent attacks?
A2: One tablet every night, especially when starting uric-acid-lowering therapy (first 6–12 months).

Q3: How fast does it stop a gout attack?
A3: Most patients feel major relief within 12–24 hours; far faster than NSAIDs.

Q4: Can I take it with allopurinol or febuxostat?
A4: Yes – in fact, it is now mandatory in guidelines to prevent flares when starting them.

Q5: Will it cause diarrhoea?
A5: Much less at 250–500mcg than old 500mcg every-hour regimens; stop if severe.

• Take with or without food
• Reduce dose in moderate kidney/liver disease or if on certain medicines (clarithromycin, cyclosporine)
• Stop and call doctor if severe diarrhoea occurs
• Not for pain other than gout unless prescribed
• Keep away from children