• Gentle 500mg extended-release metformin = better stomach tolerance
• Strong glucose lowering with empagliflozin’s added weight-loss effect
• Proven heart failure & kidney disease protection
• Convenient once-daily dosing
• Full 28-tablet pack = one month of therapy

1. Take one tablet once daily with your evening meal to minimise stomach upset
2. Swallow whole with water – never crush, chew or split
3. Take at the same time every day for steady control
4. Continue healthy diet, exercise and regular glucose checks
5. If you miss a dose, take it as soon as you remember unless it’s almost time for the next one

Q1: Is the 500mg metformin dose easier on the stomach?
A1: Yes – the lower extended-release dose causes far fewer GI side effects while still working effectively.

Q2: Will I still lose weight with the 12.5/500mg strength?
A2: Yes, most patients lose 2–4 kg thanks to empagliflozin’s calorie-loss effect.

Q3: How much does it lower A1C?
A3: Typically 1.2–1.8% reduction, depending on your starting level.

Q4: Do I still get heart and kidney protection at this dose?
A4: Absolutely – empagliflozin’s cardio-renal benefits are proven even at 10mg and 12.5mg doses.

Q5: Can my doctor increase me to 1000mg metformin later?
A5: Yes, many patients start on 500mg and step up to 1000mg if needed and tolerated.

• Use only under medical supervision with regular kidney and blood monitoring
• Drink plenty of water to reduce risk of dehydration or urinary infections
• Stop immediately and seek help if signs of lactic acidosis (muscle pain, breathing trouble, extreme tiredness) appear
• Not for type 1 diabetes or diabetic ketoacidosis
• Avoid in severe kidney impairment (eGFR <30) or active liver disease
• Discontinue before major surgery or contrast imaging studies